ESIC Exam Question Paper





mcqs 1. The pH of human blood is between
(a) 6.5-7 (b) 7.35-7.45
(c) 8-9 (d) 4.5 – 5

Normal blood pH is 7.35 to 7.45 (Slightly alkaline).



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mcqs 2.  Which of these comprise of blood?
(a)      Red Blood cell        (b) White blood cell
(c) Platelets and Plasma (d) All of these




The cells (RBC, WBC & platelets) containing fluid (plasma) that circulates through the heart and blood vessels and transport nutrients, electrolytes, hormones, vitamins, antibodies, t.-, heat and oxygen to the tissues and taking away waste matter and carbon dioxide from tissue called blood


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mcqs 3. The plasma protein that maintain oncotic pressure of blood is
(a)       Fibrinogen            (b) Albumin
(c) Globulin                  (d) Prothrombin
Oncotic pressure means osmotic pressure exerted by colloids in a solution, like plasma protein into blood. Albumin is smallest and most numerous of protein, play major role in maintaining oncotic pressure of blood
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mcqs 4. Life span of fetal RBC
(a)       80 days                   (b) 5-7 days
(c) 120 days                    (d) 100 day
mcqs 5. Life span of RBC is
(a)       120 days                   ‘(b)   80 days
(c) 200 days                    (d)    60 days
Fetal RBC has shorter life span (80 day)
compare to adult RBC (120 days).
 Fetal hemoglobin has better oxygen-binding capacity than adult hemoglobin.
Adult hemoglobin molecule composed of two . alpha and two beta chains.




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mcqs 6. Haematopoiesis in adults occur at
(a)       Red bone marrow
(b)      Yellow bone marrow
(c)       Spleen
(d)      Liver
The formation of red blood cells called erythropoiesis, which occur ‘into red bone marrow from last 3 month of uterine life to whole extra-uterine life Although not only RBC but the production and development of all type of blood cells, normally occur in the bone marrow which called hemopoiesis or haematopoiesis.
ESIC Staff Nurse 2016 (March, First Shift)
mcqs 7. The best test to assess the prognosis of the patients is:
(a)       Osmotic fragility
(b)      Hemoglobin level
(c)       Packed cell volume
(d)      Erythrocyte sedimentation rate


ESR is a nonspecific laboratory test used as a marker of inflammation and to assess the prognosis of the patients.




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mcqs 8. Immunity produced by entering the readymade antibodies into patient’s body called
(a) Active natural immunity
(b) Passive natural immunity
(c) Active acquired immunity
(d) Passive acquired immunity

Acquired immunity means the immunity acquired during life time of an individual as a results of exposure to an antigen (natural infection or vaccine) or from the passive injection of immunoglobulins..

There are two type of acquired immunity- 
(a) Active Acquired Immunity-
➡ It is the immunity or resistance developed by host body, as a result of antigenic stimulation of host body,
➡ There may be two type of active acquired immunity-
(i)      Natural active acquired immunity­” This immunity acquired or developed after a natural infection of body. ” Examples are development of immunity against typhoid, measles & chickenpox.” Infection after a natural infection of body by these infectious agents.
(ii)     Artificial active acquired immunity­” This immunity acquired or developed artificially by vaccination For example development of immunity against polio & TB by giving OPV & BCG vaccine
(b) Passive Acquired immunity-

➡ In passive immunity body cells do not take any active part in the production of antibodies, and the person is only immunized by prepared or readymade antibodies from other host.
➡ This immunity is temporary and gives less effective protection.

➡ There are two type of passive acquired immunity- 
(i)     Natural passive immunity-
“ Transmission of antibodies from mother to fetus through placenta (IgG) and through milk or colostrum of mother (IgA).
(ii)   Artificial passive immunity-
“ This immunity is produced in host by giving injection of readymade antibodies, e.g. antitoxin, ATS (anti -tetanus serum) in tetanus, IVIG (intravenous immune globulin) in myasthenia gravis etc.

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mcqs 9. The chief regulator of immune mechanism is
(a)    Plasma cell
(b)   Helper T cells 
(c). B. Lymphocyte.
(d) SuppressorT cells

HelperTcells(CD4+TcellsorinducerTcells) stimulate or regulate activity of other T cells during infection or attack of foreign body.
 ESIC Staff Nurse 2016 (March, First Shift)

mcqs 10. Which of the following terms describes a decreased number Of platelets?
(a)    Thrombectomy
(b)   Thrombocytopenia
(c)    Thrombocytopathy
(d)   Thrombocytosis 

An abnormal decrease in the number of platelets called thrombocytopenia or thrombopenia.
  Deficient function of platelets called thrombocytopathy.
  Surgical removal of a thrombus called thrombectomy.
An increase in the number of platelets called thrombocytosis


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mcqs 11. Blood clotting time (CT) is considerably prolonged in deficiency of:
(a) Vitamin B2                 (b)    Vitamin Bp
(c) Vitamin K                  (d)    Vitamin B6
ESIC Staff Nurse 2016 (March, Second Shift)
mcqs 12.  Which vitamin deficiency cause problems of clotting-
(a) Vitamin-A                 (b)     Vitamin-B
(c) Vitamin-D                 (d)    Vitamin-K
➡Vitamin K (anti-hemorrhagic factor) is needed for clotting although it directly not involved in clot
➡Vitamin K is required for synthesis of our clotting factor by hepatocytes, like clotting factor II, VII,
IX and X. 
➡Vitamin K deficiency cause increase Cl.
ESIC Staff Nurse Dehli 2009
mcqs 13. The process of tightening of the fibrin clot in such a way that the ruptured area of the
blood vessel gets smaller and smaller, thus decreasing the haemorrhage, is called.         
(a) Fibrositis                   (b)   Fibrinolysis
(c) Synarthrosis              (d)  Synercsis
Syncresis means the contraction of a gel resulting in its separation from the liquid, as a shrinkage of 
fibrin when blood clots.
It means extraction of a liquid from a gel during contraction of clot.
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mcqs 14.  Which blood group is known as universal donor ?
(a)   A                             (b)  AB
(c)  B                             (d)  O
People with O negative blood group (not contain any antigen on RBC) called universal donor.


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